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New macro bicyclic compounds, processes for their preparation and this macro bicyclis chen compounds containing the same

机译:新的大双环化合物,其制备方法以及含有该双环化合物的这种大双环化合物

摘要

the invention relates to new compounds of the general formula i makrobicyclische $f1 in the $a r1 - r6 of the ch (r7) - co2y value, and $a and a hydrogen and / or a metallionenu00e4quivalent an element of ordinal numbers 20 to 29, 31, 32, 37, 39, 42, 44, 47, 49 or 57 83 and $a r 7 a hydrogen atom or a possibly substituted with 1 to 6 hydroxygruppen,branched or unverzweigte c1 c30 - c6 - c10 alkyl -, aryl - or c7 - c30 - aralkylgruppe, with the alkyl groups may be interrupted by 1 to 10 oxygen atoms and / or by 1 to 6 co2r8 groups substituted.and $r8 hydrogen or a branched or unverzweigte c1 - c4 - alkyl - or c7 - c10 - aralkylylgruppe means $a and their salts with inorganic and / or organic bases, amino acids or aminosu00e4ureamiden. these compounds or the metallkomplexe $a the pharmaceutical means, in particular, as contrast agents for mri and radiographic applications.
机译:本发明涉及ch(r7)-co2y值的$ a r1-r6的通式i分子式$ f1的新化合物,以及$ a和氢和/或金属硫醚的序数元素20至29、31、32、37、39、42、44、47、49或57 83和$ ar 7一个氢原子或一个可能被1至6个羟基基团取代的,支链或非取代的c1 c30-c6-c10烷基- ,芳基-或c7-c30-芳烷基基团,其中的烷基可被1至10个氧原子和 /或1至6个被取代的co2r8基团和$ r8氢或支链或反式c1-c4-烷基-所间断或c7-c10-芳烷基基团是指$ a及其与无机和/或有机碱,氨基酸或氨基的盐。这些化合物或metallkomplexe是药学上的手段,尤其是作为mri和放射照相应用的造影剂。

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