首页> 外国专利> METHODS AND COMPOSITIONS FOR DETERMINING HER-2/NEUMETHODS AND COMPOSITIONS FOR DETERMINING HER-2/NEU EXPRESSION EXPRESSION

METHODS AND COMPOSITIONS FOR DETERMINING HER-2/NEUMETHODS AND COMPOSITIONS FOR DETERMINING HER-2/NEU EXPRESSION EXPRESSION

机译:测定HER-2 /神经元的方法和组成物以及测定HER-2 / NEU表达的组成物

摘要

Anti-p185?HER-2/neu¿ antibodies which are useful in the detection of HER-2/neu oncogene overexpression in biological samples are described. The antibodies are accurate and reliable in immunocytochemical or immunohistochemical assays of cell and tissue samples. Also described are methods for detecting HER-2/neu oncogene expression in a biological sample using the antibodies of the invention and a diagnostic kit comprising the antibodies. The reagents provide an accurate means of identifying certain cancer patients who have the greatest probability of relapse and/or the least likelihood of survival.
机译:描述了可用于检测生物样品中HER-2 / neu癌基因过表达的抗p185?HER-2 / neu抗体。该抗体在细胞和组织样品的免疫细胞化学或免疫组织化学测定中准确而可靠。还描述了使用本发明的抗体和包含所述抗体的诊断试剂盒检测生物学样品中HER-2 / neu癌基因表达的方法。所述试剂提供了鉴定某些癌症患者的准确方法,所述癌症患者具有最大的复发可能性和/或最小的存活可能性。

著录项

  • 公开/公告号WO9632480A3

    专利类型

  • 公开/公告日1997-05-15

    原文格式PDF

  • 申请/专利权人 AMGEN INC.;

    申请/专利号WO1996US04890

  • 发明设计人 KOSKI RAYMOND A.;

    申请日1996-04-09

  • 分类号C12N15/12;C07K16/32;C12N5/20;G01N33/53;

  • 国家 WO

  • 入库时间 2022-08-22 03:22:14

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