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Screening tests for lytic cycle antigens and antibodies to kaposi's sarcoma-associated herpesvirus

机译:溶血周期抗原和卡波西氏肉瘤相关疱疹病毒抗体的筛选测试

摘要

A screening test for Kaposi's sarcoma-associated herpesvirus in a patient involves obtaining a biological sample from the patient, and assaying for the presence of lytic cycle antigens or antibodies in the sample. In preferred embodiments, fluid samples such as peripheral blood mononuclear cells are screened for antigen of Kaposi's sarcoma-associated herpesvirus, e.g., small viral capsid antigen, or serum is screened for antibodies to that antigen. Preferred methods employ immunoblottin, immunofluorescence, or other immunoassay.
机译:对患者中卡波西氏肉瘤相关疱疹病毒的筛查测试包括从患者那里获得生物学样品,并分析样品中是否存在裂解周期抗原或抗体。在优选的实施方案中,针对诸如卡波西氏肉瘤相关疱疹病毒的抗原,例如小病毒衣壳抗原,对诸如外周血单核细胞的流体样品进行筛选,或者针对该抗原的抗体对血清进行筛选。优选的方法采用免疫印迹,免疫荧光或其他免疫测定。

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