method and device for the analysis of signals of movement and other bio signals with the theory of fractals

• 1. 可贴附并可拆卸的生物信号测量垫以及使用该生物信号测量垫的生物信号测量装置 [P] . 中国专利： CN103025233B . 2016.08.17
• 2. 可贴附并可拆卸的生物信号测量垫以及使用该生物信号测量垫的生物信号测量装置 [P] . 中国专利： CN103025233A . 2013-04-03
• 3. method and device for the analysis of signals of movement and other bio signals with the theory of fractals [P] . IT1278726B1 . 1997-11-27

  机译： 分形理论分析运动信号和其他生物信号的方法和装置

• 4. method and device for the analysis of signals of movement and other bio signals with the theory of fractals [P] . ITFI950159D0 . 1995-07-11

  机译： 分形理论分析运动信号和其他生物信号的方法和装置

• 5. BIOSIGNAL MEASUREMENT DEVICE, BIOSIGNAL MEASUREMENT METHOD, BODY-WORN MOVEMENT ASSIST DEVICE, AND MOVEMENT ASSIST METHOD [P] . 日本专利： JP2016016233A . 2016-02-01

  机译： 生物测量装置，生物测量方法，身体磨损运动辅助装置和运动辅助方法

• 1. Analysis of Acoustic Emission Signal by Fractal Theory in Aluminum Alloy Spot Welding [J] . 天津大学学报（英文版） . 2007,第003期
• 2. An effective algorithm for quick fractal analysis of movement biosignals in ambulatory monitoring [C] . Ripoli, A., Belardinelli, Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE . 1998
• 3. Biological signals analysis: A proposal of methods for quantifying patterns in biological signals. [D] . Zubrycky, Walter. 1969
• 4. The analysis of the influence of fractal structure of stimuli on fractal dynamics in fixational eye movements and EEG signal [O] . Hamidreza Namazi, Vladimir V. Kulish, Amin Akrami -1
• 5. Multifractal analysis of laser Doppler flowmetry and bio-impedancemetry signals for an integrated analysis of the cardiovascular system [O] . E. Guerreschi, A. Humeau-Heurtier, S. Bricq, 2012

• 1. A Method for Automating Signal Analysis from Therapeutic Devices [J] . Mohammed A. Eslami ,Joshua W. Guag . 智能控制与自动化（英文） . 2014,第2期
• 2. Mathematical theory of signal analysis vs. complex analysis method of harmonic analysis [J] . QIAN Tao ,ZHANG Li-ming . 高校应用数学学报B辑 . 2013,第004期
• 3. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 4. Movement and behavior analysis using neural spike signals in CA1 of rat hippocampus [J] . Hyejin An ,Kyungjin You ,Minwhan Jung . 测试科学与仪器 . 2013,第004期
• 5. 采用MedLad生物信号采集处理系统的方法验证 [C] . . 第31次全国医药行业QC小组成果发表交流会 . 2010
• 6. 基于功能型纳米材料及生物信号放大技术的新型电化学生物传感器的方法学研究 [A] . 郑莹宁 . 2018