首页> 外国专利> ISOLATED NUCLEIC ACID ENCODING HELIOBACTER PYLORI ANTIGEN, VECTOR IN WHICH IT IS COMPRISED, PURIFIED ANTIGENIC PREPARATION BEING ENCODED THEREBY, DETECTION METHOD OF THE HELIOBACTER PYLORI STRAIN PRESENCE, METHOD OF DETERMINING PRE-DIATHESIS FOR PEPTIC ULCER, METHOD OF DETERMINING PRE-DIATHESIS FOR STOMACH CARCINOMA, HELIOBACTER PYLORI MUTANT AND HELIOBACTER PYLORI STRAIN

ISOLATED NUCLEIC ACID ENCODING HELIOBACTER PYLORI ANTIGEN, VECTOR IN WHICH IT IS COMPRISED, PURIFIED ANTIGENIC PREPARATION BEING ENCODED THEREBY, DETECTION METHOD OF THE HELIOBACTER PYLORI STRAIN PRESENCE, METHOD OF DETERMINING PRE-DIATHESIS FOR PEPTIC ULCER, METHOD OF DETERMINING PRE-DIATHESIS FOR STOMACH CARCINOMA, HELIOBACTER PYLORI MUTANT AND HELIOBACTER PYLORI STRAIN

机译：编码包括幽门螺杆菌幽门螺杆菌的核酸，编码纯化的抗原制剂，测定幽门螺杆菌幽门螺杆菌的方法，确定用于糖尿病性胃溃疡的糖尿病前体的确定方法，，幽门螺杆菌突变体和幽门螺杆菌菌株

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摘要

128 kilodalton antigen helicobacter pyloris of isolated nucleic acid encode about 120-128, antigen or its segment, wherein the antigen is related with peptic ulcer. The present invention also provides detection, there are the bacterial strains of helicobacter pylori resistant to have 128 kilodalton antigens of 120-128 in the method for subject, is combined antigen or its segment and antibody of the invention with containing the detection with detectable tagA antigens or antigen polypeptide including the sample to subject. Detect bacterial strain expression TagA antigens instruction quality and peptic ulcer and gastric cancer. Mutant H. Expressive function TagA antigens are not also provided pylorus.

机译：分离的核酸的128千道尔顿抗原幽门螺杆菌编码约120-128个抗原或其片段，其中该抗原与消化性溃疡有关。本发明还提供了检测方法，该检测方法中有对幽门螺杆菌耐药的细菌菌株，具有120-128的128道尔顿抗原，所述抗原或其片段与本发明的抗体结合在一起，所述检测含有可检测的tagA抗原或包括待测样品的抗原多肽。检测细菌菌株的TagA抗原表达质量指示与消化性溃疡和胃癌有关。突变H.表达功能TagA抗原也不提供幽门。

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公开/公告号CZ9700966A3

专利类型
公开/公告日1997-10-15

原文格式PDF
申请/专利权人 VANDERBILT UNIVERSITY;ORAVAX;
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申请/专利号CZ19970000966
发明设计人 COVER TIMOTHY L.;BLASER MARTIN J.;KLEANTHOUS HARRY;TUMMURU MURALI K. R.;
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申请日1995-09-29
分类号C12N15/31;C12N15/20;C12N1/20;C07K14/205;C12Q1/68;G01N33/574;G01N33/68;A61K39/106;
国家 CZ
入库时间 2022-08-22 03:27:30

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