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EYE PREPARATION CONTAINING HYDROPHILIC POLYMER RESPONSIVE TO IONS AND INORGANIC SALT IN A RATIO, AT WHICH IT EXHIBITS LOW VISCOSITY
EYE PREPARATION CONTAINING HYDROPHILIC POLYMER RESPONSIVE TO IONS AND INORGANIC SALT IN A RATIO, AT WHICH IT EXHIBITS LOW VISCOSITY
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机译：含有对离子和无机盐有反应性的亲水性聚合物的配制品，其粘度低
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PCT No. PCT/FI95/00167 Sec. 371 Date Mar. 15, 1996 Sec. 102(e) Date Mar. 15, 1996 PCT Filed Mar. 29, 1995 PCT Pub. No. WO95/26712 PCT Pub. Date Oct. 12, 1995The present invention is directed to an ophthalmic composition in the form of a topical aqueous solution consisting essentially of an ophthalmologically active agent containing basic groups, an ion sensitive, hydrophilic polymer containing acidic groups in an amount of 0.004 to 1.5% by weight, at least one salt selected from the group of inorganic salts and buffers in a total amount of from 0.01 to 2.0% by weight, and optionally a wetting agent and a preservative, the ratio between salt and polymer being such that the solution exhibits a viscosity of less than 1000 mpas, and the pH of the solution is 4.0 to 8.0. The composition contains a sufficient amount of polymer to provide for a controlled absorption of the drug into the eye, its viscosity having been reduced to provide for better handling characteristics.
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