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Immunology measuring method null of erasutaze

机译:清除方法的免疫学测定方法无效

摘要

PURPOSE:To make the method effective as a diagnostic method of cancer, by determing the quantity of elastase 1 in a subject specimen to be measured from characteristics which are formed by manipulation similar to a subject specimen with regard to standard elastase 1 having know concentration in stead of the subject specimen. CONSTITUTION:A monoclonal antibody which recognizes antigen group A in a part separated from the combination part of elastase 1 and alpha1-antitrypsin 2 is obtained. Reaction which is approximately the same as free elastase 1 is indicated even for elastase 1, which is combined with the alpha1-antitrypsin. An accurate measurement of the elastase 1 in a liquid whose sensitivity is excellently improved is established. At the same time, stable supply of the antibody is secured. The elastase 1 combined with the alpha1-antitrypsin is peculiarly measured by using the monoclonal antibody which recognizes the combination part B of the elastase 1 and the alpha1-antitrypsin. Thus the excellent measuring system especially as a diagnostic method of cancer is established.
机译:目的:为了使该方法作为癌症的诊断方法有效,通过对与已知浓度的标准弹性蛋白酶1相似的操作,通过类似于受试者标本的处理所形成的特征,确定待测标本中的弹性蛋白酶1的量。代替标本。组成:单克隆抗体,其识别与弹性蛋白酶1和α1-抗胰蛋白酶2的结合部分分开的部分中的抗原组。即使对于与α1-抗胰蛋白酶组合的弹性蛋白酶1,也表明与游离弹性蛋白酶1大致相同的反应。建立了灵敏度大大提高的液体中弹性蛋白酶1的精确测量。同时,确保了抗体的稳定供应。通过使用识别弹性蛋白酶1和α1-抗胰蛋白酶的结合部分B的单克隆抗体,特别地测量与α1-抗胰蛋白酶结合的弹性蛋白酶1。因此,建立了特别是作为癌症诊断方法的优异的测量系统。

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