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ANGIOTENSIN-CONVERTING ENZYME INHIBITOR AND INSULIN-LIKE-ACTING AGENT CONTAINING TRANS-10-HYDROXY-DECENOIC ACID INCLUDED IN ROYAL JELLY AS ACTIVE INGREDIENT
ANGIOTENSIN-CONVERTING ENZYME INHIBITOR AND INSULIN-LIKE-ACTING AGENT CONTAINING TRANS-10-HYDROXY-DECENOIC ACID INCLUDED IN ROYAL JELLY AS ACTIVE INGREDIENT
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机译：包含在果冻中作为活性成分的反式-10-羟基癸酸的血管紧张素转换酶抑制剂和类似胰岛素的活性剂
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摘要
PROBLEM TO BE SOLVED: To obtain an angiotensin-converting enzyme inhibitor and an insulin- like acting agent which contain a component included in royal jelly and are useful in prevention and therapy of hypertension and diabetes safety without side effect. ;SOLUTION: These preparatioins contain trans-10-hydroxy-decenoic acid (addreviated as HDA) as an active ingredient. HDA has inhibitory action on an angiotensin-converting enzyme and an inhibitory action on lipolysis in fat cells to promote fat synthesis like insulin. HDA is mixed with a carrier, an excipient, diluent and the like appropriatelhy to prepare tablets, capsules, grains, injection solution, suppository and the like. When it is used as an angiotensin- converting enzyme inhibitor, the daily dose is 100-200mg/man (60kg body weight) twice a day while the dose is 100-200mg/man (60kg body weight) about three times a day, when it is used as an insulin-like acting agent.;COPYRIGHT: (C)1997,JPO
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