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PHARMACEUTICAL COMPOSITIONS, FOR INHIBITING VASOMOTOR SYMPTOMS AND ATTENDING PSYCHOLOGICAL DISTURBANCES SURROUNDING POST-MENOPAUSAL SYNDROME CONTAINING 2-PHENYL-3-AROYL-BENZOTHIOPHENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
PHARMACEUTICAL COMPOSITIONS, FOR INHIBITING VASOMOTOR SYMPTOMS AND ATTENDING PSYCHOLOGICAL DISTURBANCES SURROUNDING POST-MENOPAUSAL SYNDROME CONTAINING 2-PHENYL-3-AROYL-BENZOTHIOPHENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
A method of inhibiting vasomotor symptoms and attending psychological disturbances surrounding post-menopausal syndrome comprising administering to a female human in need of treatment an effective amount of a compound having the formula CHEM wherein R1 and R3 are independently hydrogen, -CH3, CHEM wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
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机译:抑制绝经后综合症周围的血管舒缩症状和心理障碍的方法,包括对需要治疗的女性给予有效量的具有式的化合物,其中R 1和R 3独立地为氢,-CH 3,其中Ar是任选取代的苯基; R 2选自吡咯烷,六亚甲基氨基和哌啶子基;或其溶剂化物的可药用盐。
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