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Wildness inter- - from roikin 6 the mutation which possesses the biological activity which is improved inter- - roikin 6

机译:野生互济鼠6之间的突变具有改善互济鼠6的生物活性。

摘要

The present invention is drawn to mutant interleukin 6, which has the amino acid arginine in position 176, replacing serine in position 176 with wild-type interleukin 6. The mutant interleukin 6 of the present invention has greater biological activity than the wild-type protein. The present invention is further drawn to methods of making mutant interleukin 6, having arginine at position 176 and methods of using the same.
机译:本发明涉及突变型白介素6,其在176位具有氨基酸精氨酸,用野生型白介素6代替了176位的丝氨酸。本发明的突变白介素6具有比野生型蛋白更大的生物学活性。 。本发明进一步涉及制备在176位具有精氨酸的突变型白介素6的方法及其使用方法。

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