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Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon

机译:聚(环氧烷)氨基酸共聚物和基于其的药物载体和带电共聚物

摘要

Copolymers of poly(alkylene oxides) and amino acids or peptide sequences are disclosed, which amino acids or peptide sequences have pendant functional groups that are capable of being conjugated with pharmaceutically active compounds for drug delivery systems and cross- linked to form polymer matrices functional as hydrogel membranes. The copolymers can also be formed into conductive materials. Methods are also disclosed for preparing the polymers and forming the drug conjugates, hydrogel membranes and conductive materials.
机译:公开了聚(环氧烷)与氨基酸或肽序列的共聚物,其中氨基酸或肽序列具有侧基官能团,所述侧基官能团能够与用于药物递送系统的药物活性化合物缀合并交联以形成具有如下功能的聚合物基质:水凝胶膜。共聚物也可以形成导电材料。还公开了制备聚合物并形成药物缀合物,水凝胶膜和导电材料的方法。

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