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Polypeptides, rich in proline, which inhibit the NADPH oxidase system

机译:富含脯氨酸的多肽,可抑制NADPH氧化酶系统

摘要

Polypeptides comprising the sequence PXXPPXP (wherein X is an amino acid), especially PAVPPRP or QPAVPPHPS, which inhibits at least one interaction between p47phox and p67phox of the NADPH oxidase system, and homologues thereof, are described. The polypeptides may be used in the therapy of inflammatory states.
机译:描述了包含序列PXXPPXP(其中X是氨基酸)的多肽,尤其是PAVPPRP或QPAVPPHPS,其抑制NADPH氧化酶系统的p47phox和p67phox之间的至少一种相互作用,及其同源物。所述多肽可用于炎性状态的治疗。

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