首页> 外国专利> Condensed dibenzoxazepines or dibenzothiazepines useful as prostaglandin-e2 antagonists

Condensed dibenzoxazepines or dibenzothiazepines useful as prostaglandin-e2 antagonists

机译:缩合的二苯并x氮平或二苯并噻氮平可用作前列腺素-e2拮抗剂

摘要

The present invention provides substituted dibenzoxazepine compounds of Formula I: IMAGE which are useful as analgesic agents for the treatment of pain, and as prostaglandin-E2 antagonists for the treatment of prostaglandin-E2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin-E2 mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
机译:本发明提供了具有化学式I的取代的二苯并x庚因化合物:用作治疗疼痛的止痛药,以及用作治疗前列腺素-E2介导的疾病的前列腺素-E2拮抗剂,包含治疗有效量的药物组合物式I的化合物与可药用载体的组合,用于消除或减轻动物疼痛的方法以及用于治疗动物中前列腺素E2介导的疾病的方法,包括给予治疗有效量的化合物式I对动物的影响

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