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the dna sequence of the insert carlubo codifying for a complete protein heat shch of forda (candida albicans strain cansp 70) atcc 20955 and derivatives which can be used for both for diagnostic purposes that profilatticonell'infection with c. albicans.
the dna sequence of the insert carlubo codifying for a complete protein heat shch of forda (candida albicans strain cansp 70) atcc 20955 and derivatives which can be used for both for diagnostic purposes that profilatticonell'infection with c. albicans.
the invention relates to: (1) the use of the dna sequence of carlv130 as oligonucleotidi for use in amplification reaction chain or polymerase chain reaction (pcr); 2) the u.s.the dna sequence of carlv130 as probes oligonueleotidiche to use for the typing / diagnosis of candida and candidiasis; 3) the use of the dna sequence of carlvi30 and that polipeptell you deducted as possible targets of rna antisenso or antibiotics or chemoterapici active on candida species that possess this sequence; (4) the use of the sequence of amino acids of the cahsp70or parts of it to obtain antisera or monoclonal antibodies in order to develop immunological methods that reveal the presence of c.albicans and related species, and / or cahsp70 issued by the parasite; (5) the use of (or synthetic polypeptides expressed in vivo) derived from the sequence of the cahsp70.as components of diagnostic systems able to reveal the presence of cahsp70 produced by the parasite; 6) the use of the amino acid sequence of casph70 or parts of it to obtain antisera and / ormonoclonal antibodies to obtain vaccine preparations or to develop treatments for prophylactic purposes and / or therapeutic; 7) the use of (or synthetic polypeptides expressed in vivo)derived from the sequence of the casph70 as components of vaccine preparations or preparations used for prophylactic and / or therapeutic.
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