首页> 外国专利> Drug for human use having a contraceptive and menstrual cycle-regulating action, a preventive and therapeutic oncostatic action in tumours of the breast and melanomas, and an antikinetose action and method of synthesis

Drug for human use having a contraceptive and menstrual cycle-regulating action, a preventive and therapeutic oncostatic action in tumours of the breast and melanomas, and an antikinetose action and method of synthesis

机译:用于人类的药物,具有避孕和月经周期调节作用,在乳腺和黑素瘤的肿瘤中具有预防和治疗上的抑癌作用,以及抗动酶作用和合成方法

摘要

This invention relates to a drug for human use, having a contraceptive and menstrual cycle-regulating action characterised in that it provides for the use of N-acetyl- 5-methoxytryptamine or melatonin in a daily dose of 100- 200 mg, N-acetyl-2-bromo-5-methoxytryptamine or 2- bromomelatonin in a daily dose of 25-50 mg, N-acetyl-2- iodo-5-methoxytryptamine or 2-iodomelatonin in a daily dose of 20-40 mg in association with a progestin. Administration is continued for 23 days using the association of 2-iodomelatonin and/or melatonin and/or 2- bromomelatonin and a progestin, followed by 5 days administration of the 2-iodomelatonin and/or melatonin and/or 2-bromomelatonin alone; having a preventive and therapeutic oncostatic action in tumours of the breast and melanomas, characterised by the use of 2- iodomelatonin, melatonin and 2-bromomelatonin respectively in doses of 20-40 mg, 100-200 mg, 25-50 mg per day; having an antikinetose action, characterised by the use of 2-iodomelatonin in a dose of 2.5 mg per day, melatonin in a dose of 10 mg per day and 2-bromomelatonin in a dose of 3.5 mg per day, alone and/or in association with acetyl coenzyme A-(AcCOA)- in a dose of 8-10 mg per day.
机译:本发明涉及具有避孕和月经周期调节作用的人用药物,其特征在于它以每天剂量100-200mg的N-乙酰基-5-甲氧基色胺或褪黑激素的用途提供。日剂量为25-50 mg的-2-溴-5-甲氧基色胺或2-溴褪黑素,日剂量为20-40 mg的N-乙酰基-2-碘5-甲氧基色胺或2-碘降钙素与孕激素。使用2-碘褪黑激素和/或褪黑激素和/或2-溴褪黑激素和孕激素的联合给药持续23天,然后单独使用2-碘褪黑激素和/或褪黑激素和/或2-溴褪黑激素联合给药5天。在乳房和黑色素瘤的肿瘤中具有预防和治疗抗癌作用,其特征在于每天分别以20-40 mg,100-200 mg,25-50 mg的剂量使用2-碘褪黑激素,褪黑激素和2-溴褪黑激素;具有抗动酶作用,其特征在于单独和/或联合使用每天剂量为2.5 mg的2-碘褪黑激素,每天剂量为10 mg的褪黑激素和每天剂量为3.5 mg的2-溴褪黑激素乙酰辅酶A-(AcCOA)-的剂量为每天8-10 mg。

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