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PERCUTANEOUS ADMINISTRATION OF SPIRONOLACTONE AS SYSTEMICALLY ACTIVE ANTI-ANDROGEN AND PREPARATION COMPOSITION FOR LOCAL THERAPY OF ACNE VULGARIS, SEBORRHEIC DERMATITIS AND HIRSUTISM
PERCUTANEOUS ADMINISTRATION OF SPIRONOLACTONE AS SYSTEMICALLY ACTIVE ANTI-ANDROGEN AND PREPARATION COMPOSITION FOR LOCAL THERAPY OF ACNE VULGARIS, SEBORRHEIC DERMATITIS AND HIRSUTISM
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机译:螺内酯作为全身活性抗雄激素的经皮给药及寻常性痤疮,脂溢性皮炎和湿疹的局部治疗的制剂组成
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摘要
PURPOSE: To obtain a spironolactone-contg. preparation composition for application to human skin site(s) suffered from acne, seborrheic symptom or hirsutism for the purpose of the lesion's effective therapy. ;CONSTITUTION: This preparation composition for the local application of spironolactone as active ingredient for the purpose of mitigating androgen activity raised in the skin, comprises a safe and effective amount of spironolactone (at 0.1-10 wt.%), a penetration potentiator containing an N,N-di(lower alkyl)laurinamide and a pharmaceutically acceptable vehicle.;COPYRIGHT: (C)1995,JPO
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