首页> 外国专利> Intermediate circuit between a logic circuit at a low voltage and an output stage at a high voltage produced in a standard cmos technology.

Intermediate circuit between a logic circuit at a low voltage and an output stage at a high voltage produced in a standard cmos technology.

机译:以标准cmos技术生产的低压逻辑电路和高压输出级之间的中间电路。

摘要

The present invention relates to a new utilization of a peptide substance, said utilization being characterized in that use is made of a peptide substance comprising in its structure: (a) a first fragment having the formula Asx-A1?-A2?, (F1?), wherein Asx is Asp ou Asn, A1? is Gly, MeGly, EtGly ou Aib, A2? is Arg, Dbu, His, Lys ou Orn, and (b) a second fragment of formula: A3?-Cys-A4?-Asx, (F2?), wherein A3? is Leu, Ile, Nle, Val, Nva, Ahe, Acp or Cle, A4? is Leu, Ile, Nle, Val, Nva, Ahe, Acp or Cle, and Asx is Asp or Asn as indicated hereabove, the second fragment (F2?) being closer to the terminal C-extremity than the first fragment (F1?), for the preparation of a cytoprotector medicament useful against cytotoxic agressions. Amongst said peptide substances, those which are new are also useful as anti-megacaryocytic agents.
机译:本发明涉及一种肽物质的新用途,所述用途的特征在于使用了一种肽物质,该肽物质的结构包括:(a)具有式Asx-A1β-A2β的第一片段,(F1 α),其中Asx是Asp ou Asn,A1?是Gly,MeGly,EtGly ou Aib,A2吗?是Arg,Dbu,His,Lys ou Orn,以及(b)下式的第二个片段:A3′-Cys-A4′-Asx,(F2′),其中A3′。是Leu,Ile,Nle,Val,Nva,Ahe,Acp或Cle,A4?如前所述,Leu,Ile,Nle,Val,Nva,Ahe,Acp或Cle是Asp或Asp是Asp或Asn,第二个片段(F2′)比第一个片段(F1′)更靠近末端C-末端。用于制备抗细胞毒性侵袭的细胞保护剂。在所述肽物质中,新的肽物质也可用作抗巨核细胞活性剂。

著录项

  • 公开/公告号JPH07506587A

    专利类型

  • 公开/公告日1995-07-20

    原文格式PDF

  • 申请/专利权人

    申请/专利号JP19930519954

  • 发明设计人

    申请日1993-05-18

  • 分类号C07K7/06;A61K38/00;C07K1/04;C07K7/08;C07K14/745;

  • 国家 JP

  • 入库时间 2022-08-22 04:30:52

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