首页>
外国专利>
Novel Chelating Agents, Complexes Comprising the Chelating Agents and Metal Atoms, and Diagnostic Agents Comprising the Compounds (NOVEL CHELATING AGENT, COMPLEX COMPOUND COMPOSED OF SAID AGENT AND METALLIC ATOM, AND DIAGNOSTIC AGENT CONTAINING SAID COMPOUND)
Novel Chelating Agents, Complexes Comprising the Chelating Agents and Metal Atoms, and Diagnostic Agents Comprising the Compounds (NOVEL CHELATING AGENT, COMPLEX COMPOUND COMPOSED OF SAID AGENT AND METALLIC ATOM, AND DIAGNOSTIC AGENT CONTAINING SAID COMPOUND)
The present invention relates to a compound represented by the following general formula (I), a complex compound composed of the compound and a metal atom, and a diagnostic agent comprising the complex compound, wherein the compound (I) mentioned above is useful as a chelating agent and is complex The compound shows better properties as a contrast medium for imaging.;Wherein m is an integer from 1 to 3; R 1 and R 2 are the same or different and are each hydrogen atom or lower alkyl; R 3 , R 4 , R 5 and R 6 are the same or different and each is hydroxy or the following general formula (II),; (Wherein n is 0 or 1; X is -NH- or -O-; Y is alkylene; A is hydrogen atom, lower alkyl, lower alkoxy, halogen atom or trifluoromethyl B is alkyl or alkenyl); Provided that if two or three of R 3 , R 4 , R 5 and R 6 are hydroxyl groups, and two of them are hydroxyl groups, then R 3 and R 5 are hydroxy and R 4 and R 6 are hydroxyl In case of oxy it is excluded.
展开▼
