首页> 外国专利> POLYUNSATURATED FATTY ACID BASED DRUGS, IN PARTICULAR DOCOSAHEXAENOIC ACID, FOR USE AS PLATELET AGGREGATION INHIBITORS AND AGAINST ESSENTIAL FATTY ACID DEFICIENCIES OF THE BRAIN

POLYUNSATURATED FATTY ACID BASED DRUGS, IN PARTICULAR DOCOSAHEXAENOIC ACID, FOR USE AS PLATELET AGGREGATION INHIBITORS AND AGAINST ESSENTIAL FATTY ACID DEFICIENCIES OF THE BRAIN

机译：以多不饱和脂肪酸为基础的药物，尤其是二十二碳六烯酸，用作血小板凝集抑制剂和对抗大脑必需的脂肪酸缺乏症

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摘要

Novel essential fatty acid based drugs comprising a substantial proportion of docosahexaenoic acid (DHA) in the class of fatty acids esterified in position sn-2 of phosphatidylcholines (PCDHAs) acetylated in position sn-1, or lysophosphatidylcholines (lyso-PCDHAs), or DHA-triglycerides esterifed in position sn-2 and acetylated in positions sn-1 and sn-3. Said drugs are useful for treating cardiovascular diseases, including atheromatous disease, and essential fatty acid deficiency, particularly in the brain.

机译：新型的基于必需脂肪酸的药物，包括在sn-1位置被乙酰化的磷脂酰胆碱（PCDHAs）的sn-2位置酯化的脂肪酸中的二十二碳六烯酸（DHA）或溶血磷脂酰胆碱（lyso-PCDHAs）或DHA -甘油三酸酯在sn-2位置被酯化并且在sn-1和sn-3位置被乙酰化。所述药物可用于治疗心血管疾病，包括动脉粥样硬化疾病和必需脂肪酸缺乏症，特别是在大脑中。

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公开/公告号WO9412170A2

专利类型
公开/公告日1994-06-09

原文格式PDF
申请/专利权人 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;IMEDEX;BAYON YVES;CROSET MARTINE;LAGARDE MICHEL;LECERF JEAN;THIES FRANK;TAYOT JEAN-LOUIS;CHIROUZE VÉRONIQUE;
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申请/专利号WO1993FR01158
发明设计人 BAYON YVES;CROSET MARTINE;LAGARDE MICHEL;LECERF JEAN;THIES FRANK;TAYOT JEAN-LOUIS;CHIROUZE VÉRONIQUE;
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申请日1993-11-24
分类号A61K31/23;
国家 WO
入库时间 2022-08-22 04:40:48

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