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New transdominant TAT variants of the human immunodeficiency virus
New transdominant TAT variants of the human immunodeficiency virus
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机译：人类免疫缺陷病毒的新的TTA变异型
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摘要
New variants (I) of the TAT protein of HIV, or their fragments, contain at least one mutation involving a change in the natural amino acid at positions 38, 40, 41, 45, 47 or 59-72, provided always that amino acids 41 and 47 are not Ala. Also new are (1) DNA fragments (II) encoding (I); (2) expression cassettes contg. (II) under control of expression elements; (3) prokaryotic or eukaryotic cells contg. these cassettes and (4) variant TAT proteins expressed by (II).
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