首页> 外国专利> pctd plasmid isolated from chlamydia trachomatis serotipo dgene and protein encoded by the recombinant plasmids for the expression of these; genes in heterologous systems such as recombinant proteins, the mergerpreparation of the recombinant proteins and their use in the formulation of vaccines and / or diagnostic

pctd plasmid isolated from chlamydia trachomatis serotipo dgene and protein encoded by the recombinant plasmids for the expression of these; genes in heterologous systems such as recombinant proteins, the mergerpreparation of the recombinant proteins and their use in the formulation of vaccines and / or diagnostic

机译:从沙眼衣原体血清型沙眼衣原体d基因分离的pctd质粒和由重组质粒编码的表达这些质粒的蛋白;异源系统中的基因,例如重组蛋白,重组蛋白的合并制备及其在疫苗和/或诊断中的用途

摘要

it is described a plasmid isolated from chlamydia trachomatis comprising eight genes coding proteins useful in the formulation of vaccines or diagnostic tests for the determination of bacteria orspecific antibodies generated during the course of infection by c.trachomatis; in particular, it is described the fusion recombinant protein ms2 - pgp3d comprising sequences polipeptidiche coded by pcts and immunogeniche during infections in man.in addition, a method is described for the preparation of such a protein in e. coli.
机译:描述了一种从沙​​眼衣原体分离的质粒,该质粒包含八个编码蛋白质的基因,这些蛋白质可用于疫苗的制备或诊断试验,用于确定沙眼衣原体感染过程中产生的细菌或特异性抗体。特别地,描述了融合重组蛋白ms2-pgp3d,其包含在人感染期间由pcts和免疫原性编码的多肽序列的脂肽。另外,描述了一种在大肠杆菌中制备这种蛋白的方法。大肠杆菌。

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