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Topical pharmaceutical compsn. - contg. crosslinked cationic polymer and has enhanced skin penetration effects
Topical pharmaceutical compsn. - contg. crosslinked cationic polymer and has enhanced skin penetration effects
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机译:外用药物组合。 -续交联的阳离子聚合物,并具有增强的皮肤渗透效果
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摘要
A new topical pharmaceutical compsn. having enhanced penetration through the skin comprises (a) a safe and effective amt. of a pharmaceutical active; and (b) from 0.1-10.0% of a high molecular wt. crosslinked cationic polymer of the formula (A)l(B)m(C)n where the polymer contains a crosslinking agent, where (A) is dialkylaminoalkyl acrylate monomer or its quat. ammonium or acid addn. sa (B) is a dialkylaminoalkyl methacrylate monomer or its quat. ammonium or acid addn. sa (C) is acrylamide; l is an integer of 0 or greater; m is an integer of 1 or greater; n is an integer of 0 or greater.
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