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Process for the production of esters of 1 - methyl - 10a - methoxyl - read milysergol
Process for the production of esters of 1 - methyl - 10a - methoxyl - read milysergol
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机译：制备1-甲基-10a-甲氧基的酯的方法-读麦来谷醇
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摘要
The invention relates to the manufacture of 1-methyl-10 alpha -methoxylumilysergol esters of formula: IMAGE in which R is a carboxylic acid residue RCOOH up to C10, which is optionally halogenated. The process comprises the following steps: a) Ipomoea seeds are extracted by means of a solvent chosen from dichloromethane and dichloroethane and the extract is dried thereby obtaining the corresponding total dry extract of the plant material, also comprising lysergol but not isolated from the complex; b) this total dry extract is treated, in liquid suspension, with a methylating agent to convert the lysergol which it contains to 1-methyllysergol; c) the 1-methyllysergol which is thus obtained as extractive compound is separated from the said extract; d) the extractive 1-methyllysergol is converted to 1-methyl-10 alpha -methoxylumilysergol by exposure to a UV lamp; and e) the 1-methyl-10 alpha -methoxylumilysergol is reacted with an organic acid R-COOH defined above to give the ester of formula I.
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机译： N-[n-（3,3-dimetilbutil）-L-α-天冬氨酰]-L-苯丙氨酸甲酯的分离和纯化方法，生产N-[n-（3），3-dimetilbutil的方法）-L-α-天冬氨酰]-L-苯丙氨酸甲酯或N-[n-（3,3--dimetilbutil）-L-α-天冬氨酰]-L-苯丙氨酸甲酯和N，n'- di （3,3-dimetilbutil）-APM.APM衍生物和甜味剂
