• 主题
高级搜索  >
历史搜索 清空历史
首页> 外国专利> 3,4-Di-(hydro)-2H,6H-pyrimido not 2,1-b not 1,3 thiazine derivatives and 1,2,3,4-tetra-(hydro)-pyrimidin-2-thiones, process for their preparation and medicament containing them

3,4-Di-(hydro)-2H,6H-pyrimido not 2,1-b not 1,3 thiazine derivatives and 1,2,3,4-tetra-(hydro)-pyrimidin-2-thiones, process for their preparation and medicament containing them

机译：3,4-二-（氢）-2H，6H-嘧啶不是2,1-b不是1,3噻嗪衍生物和1,2,3,4-四-（氢）-嘧啶-2-硫酮的制备方法他们的制剂和包含它们的药物

页面导航
  • 摘要
  • 著录项
  • 相似文献

摘要

The invention relates to new dihydropyrimidothiazine derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same and new intermediates useful in the preparation of the said dihydropyrimidothiazine derivatives. The new dihydropyrimidothiazine derivatives of the general formula I, IMAGE I wherein R1 represents C1-6 alkoxy, amino or phenylamino, R2 stands for C1-6 alkyl or phenyl, R3 represents hydrogen or C1-6 alkyl, and R4 denotes C1-11 alkyl or phenyl optionally bearing one or more identical or different substituent/s/ selected from halogen, nitro, amino, di-(C1-6 alkyl)-amino, C1-6 alkyl, C1-6 alkoxy and hydroxy, and pharmaceutically acceptable acid addition salts thereof exert valuable antianginal and/or antiinflammatory effect/s/ and are useful in therapy.
机译：本发明涉及新的二氢嘧啶并噻嗪衍生物，其制备方法，包含相同的药物组合物和用于制备所述二氢嘧啶并噻嗪衍生物的新中间体。通式I的新的二氢嘧啶噻嗪衍生物，其中R 1代表C 1-6烷氧基，氨基或苯氨基，R 2代表C 1-6烷基或苯基，R 3代表氢或C 1-6烷基，R 4代表C 1-任选地带有一个或多个选自卤素，硝基，氨基，二-（C 1-6烷基）-氨基，C 1-6烷基，C 1-6烷氧基和羟基的一个或多个相同或不同取代基的烷基或苯基，以及药学上可接受的其酸加成盐发挥有价值的抗心绞痛和/或抗炎作用，并且可用于治疗。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号