首页> 外国专利> Process for preparing a stabilized, aqueous enzyme dispersion, a stabilized, aqueous enzyme dispersion which is prepared in this process, and a clear solution which comprises an enzyme and a water-soluble polymer for use in the process

Process for preparing a stabilized, aqueous enzyme dispersion, a stabilized, aqueous enzyme dispersion which is prepared in this process, and a clear solution which comprises an enzyme and a water-soluble polymer for use in the process

机译:制备稳定的水性酶分散液的方法,在该方法中制备的稳定的水性酶分散液以及用于该方法的包含酶和水溶性聚合物的澄清溶液

摘要

A convenient method for preparing a stabilized aqueous enzyme dispersion comprises: (1) precipitating a water-soluble polymer from aqueous solution to form an aqueous dispersion, and (2) before, during or after (1), contacting the dissolved or dispersed polymer with an aqueous solution or fine aqueous dispersion of enzyme. Using this method, substantial improvement of the enzyme stability during storage can be obtained with surprisingly little polymer (relative to enzyme). And enzyme stabilization can, surprisingly, even be obtained by contacting precipitated polymer with dissolved enzyme. The stabilizing effect therefore appears not to be due (or at least not primarily due) to encapsulation.
机译:一种制备稳定的酶水分散体的简便方法包括:(1)从水溶液中沉淀出水溶性聚合物以形成水分散体,以及(2)在(1)之前,之中或之后,使溶解或分散的聚合物与酶的水溶液或细水分散体。使用这种方法,可以用出乎意料地少的聚合物(相对于酶)获得在储存过程中酶稳定性的显着改善。令人惊讶地,甚至可以通过使沉淀的聚合物与溶解的酶接触来获得酶稳定作用。因此,稳定作用似乎不是(或至少主要不是)封装引起的。

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