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Monoclonal antibody, process for preparing it, and diagnostic kit which is suitable for detecting and diagnosing human non-small cell lung cancer using the monoclonal antibody
Monoclonal antibody, process for preparing it, and diagnostic kit which is suitable for detecting and diagnosing human non-small cell lung cancer using the monoclonal antibody
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机译:单克隆抗体,其制备方法和适用于使用该单克隆抗体检测和诊断人非小细胞肺癌的诊断试剂盒
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摘要
Monoclonal antibodies 703D4 and 704A1 detect human non-small cell lung cancer (non-SCLC) and distinguish non-SCLC from all other types of lung cancer and normal tissue cells. These two antibodies may be utilized in kit form to distinguish non-SCLC from other forms of lung cancer. These monoclonal antibodies bind to S35 methionine-incorporating protein doublets under reduced and unreduced conditions. The determinants bound by these antibodies on the 31 kiladalton protein are independent of each other as determined in radiolabelled competition assays.
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