首页>
外国专利>
ANTIBODY SPECIFIC TO A CELL SURFACE CARBOHYDRATE ANTIGEN FOUND ON LUNG CARCINOMA CELLS, METHODS OF DIAGNOSIS AND KITS
ANTIBODY SPECIFIC TO A CELL SURFACE CARBOHYDRATE ANTIGEN FOUND ON LUNG CARCINOMA CELLS, METHODS OF DIAGNOSIS AND KITS
展开▼
机译:肺癌细胞上发现的一种细胞表面碳水化合物抗原的抗体,诊断方法和试剂盒
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention is concerned with two novel monoclonal antibodies which define carbohydrate antigens associated with human non-small cell lung carcinomas ("NSCLC") and certain other human carcinomas. The antibodies bind to normal human cells to a much lesser degree than to tumor cells. The antibodies find use in diagnostic methods such as the detection of malignant cells associated with NSCLC and in therapeutic methods. The invention also comprises a method for determining the presence of a malignant condition in the lung of a subject. The method involves examining tissue from the subject for the presence of antigens which are Lex or Ley antigen or which have the characteristics of Ley and Lex.
展开▼