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PROCESS FOR PURIFYING ALKYLATED AND HYDROXYALKYLATED CYCLODEXTRINS AND FOR REDUCING THEIR UNSUBSTITUTED CYCLODEXTRIN CONTENT

机译：纯化烷基化和羟烷基化环糊精的工艺及其还原未取代的环糊精含量的方法

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摘要

Toxicity caused by contamination and nephrotoxic action of unsubstd. cyclodextrins is eliminated when their concn. is reduced by adsorption or selective complexing below toxic levels in prepns. contg. alkylated or hydroxyalkylated cyclodextrins. These prepns. are administered in large doses, parenterally as injections or infusions. They contain 6, 7, or 8 membered substd. (alpha,beta, gamma)cyclodextrins as solubility enhancers, carriers or preservatives

机译：由污染引起的毒性和肾毒性作用不明显。当环糊精浓度消除时。通过吸附或选择性络合降低到低于制备前的毒性水平。续烷基化或羟烷基化的环糊精。这些准备。以大剂量，肠胃外注射或输注的形式给药。它们包含6、7或8个成员substd。（α，β，γ）环糊精作为溶解度增强剂，载体或防腐剂

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公开/公告号HUT56584A

专利类型
公开/公告日1991-09-30

原文格式PDF
申请/专利权人 CYCLOLAB CYCLODEXTRIN KUTATO-FEJLESZTOE LEANYVALLALATHU;
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申请/专利号HU19900001789
发明设计人 SZENTELAJOSHU;WEISZFEILERVIKTORHU;SZEJTLIJOZSEFHU;JICSINSZKYLASZLOHU;UJHAZYANDRASHU;
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申请日1990-03-22
分类号C08B37/16;C07B63/04;
国家 HU
入库时间 2022-08-22 05:58:28

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