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Detection of quality of retinal subspecies and gene defects of tumor retinal subspecies by using retinal subspecies gene probe

机译:用视网膜亚种基因探针检测视网膜亚种的质量和肿瘤视网膜亚种的基因缺陷

摘要

A Method of and a kit for detecting the predisposition to retinoblastoma. A method for detecting a defect in the retinoblastoma gene in retinoblastoma, osteosarcoma, fibrosarcoma, melanoma, soft tissue sarcoma, small-cell carcinoma and mammary tumors. The method includes hybridizing a retinoblastoma gene probe to DNA extracted from target tissue and then determining binding of the probe to the DNA. The target tissue can be tumor or non-tumor tissue and from a fetus to an adult. Further there are DNA probes of 4.6, 3.8, and 0.9 kb.
机译:一种检测视网膜母细胞瘤易感性的方法和试剂盒。一种检测视网膜母细胞瘤,骨肉瘤,纤维肉瘤,黑色素瘤,软组织肉瘤,小细胞癌和乳腺肿瘤中视网膜母细胞瘤基因缺陷的方法。该方法包括使成视网膜细胞瘤基因探针与从靶组织提取的DNA杂交,然后确定探针与DNA的结合。靶组织可以是肿瘤或非肿瘤组织,并且可以从胎儿到成年。此外,还有4.6、3.8和0.9 kb的DNA探针。

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