首页> 外国专利> MEASUREMENT OF PGE 2? (PROSTAGLANDIN E 2?) LEVELS IN PATIENTS WITH CHRONIC INFLAMMATORY BOWEL DISEASE

MEASUREMENT OF PGE 2? (PROSTAGLANDIN E 2?) LEVELS IN PATIENTS WITH CHRONIC INFLAMMATORY BOWEL DISEASE

机译:PGE 2的测量? (前列腺素E 2?)慢性炎症性肠病患者的水平

摘要

The present invention relates to a method for (1) to assess the disease activity in patients with chronic inflammatory intestinal disorders (IBD), namely ulcerative colitis (UC) and Crohn's colitis ( CC) respectively, and (2) to provide (a) the result of medical treatment in the case of severe active disease in which acute or subacute surgery may be another solution, plus (b) the risk of relapse in patients without symptoms who want to stop taking drugs to prevent relapse. The present invention further relates to a kit for use in the method described above. The test kit comprises dialysis bags designed for oral administration and / or rectal introduction, in addition to essential and specific test substances used in the radioimmunoassay of the presence of PGE2 in the content of the dialysis bags.
机译:本发明涉及一种方法,该方法用于(1)评估分别患有溃疡性结肠炎(UC)和克罗恩结肠炎(CC)的慢性炎性肠病(IBD)患者的疾病活动,以及(2)提供(a)严重活动性疾病的医疗结果,而急性或亚急性手术可能是另一种解决方案,再加上(b)没有症状而想要停止服用药物预防复发的无症状患者的复发风险。本发明还涉及用于上述方法的试剂盒。除了用于放射免疫测定中透析袋中PGE2的存在的基本和特定测试物质外,该测试套件还包括设计用于口服和/或直肠引入的透析袋。

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