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Process for the preparation of a stable aqueous fat emulsion and its use in parenterally administered complete nutrient solutions

机译:稳定的水性脂肪乳剂的制备方法及其在胃肠外给药完全营养液中的用途

摘要

1. A process for the preparation of a stable aqueous fat emulsion for use in solutions for parenteral alimentation, by emulsifying the fat under high pressure and with the use of phospholipids, in particular lecithins, as the emulsifier, wherein, in addition to the phospholipid used as the emulsifier, ubidecarenone is used as the auxiliary emulsifier in a weight ratio of phospholipid to ubidecarenone of from 150:1 to 7.5:1, and the weight of the two emulsifiers together is in a ratio to the weight of the amount of fat to be emulsified of from 1:7 to 1:30.
机译:1.一种制备稳定的水性脂肪乳剂的方法,其用于肠胃外营养的溶液中,方法是在高压下乳化脂肪,并使用磷脂,特别是卵磷脂作为乳化剂,其中,除磷脂外用作乳化剂时,泛肽烯酮用作辅助乳化剂,磷脂与泛肽烯酮的重量比为150:1至7.5:1,两种乳化剂的重量之和与脂肪量的重量之比从1:7到1:30被乳化。

著录项

  • 公开/公告号EP0211204B1

    专利类型

  • 公开/公告日1990-10-10

    原文格式PDF

  • 申请/专利权人 LEOPOLD PHARMA GMBH;

    申请/专利号EP19860108465

  • 发明设计人 GROKE KARL;POLZER JOSEF;

    申请日1986-06-20

  • 分类号A61K9/10;A61K31/23;A61K37/18;A61K47/00;

  • 国家 EP

  • 入库时间 2022-08-22 06:14:34

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