首页> 外国专利> PREPARATION PROCESS OF PHARMACEUTICAL COMPOSITIONS COMPOSING AN EXTRAGRANULAR EXCIPIENT, INSOLUBLE HYGROSCOPE IN WATER AND AN ACTIVE INGREDIENT, IN PARTICULAR CIMETIDINE

PREPARATION PROCESS OF PHARMACEUTICAL COMPOSITIONS COMPOSING AN EXTRAGRANULAR EXCIPIENT, INSOLUBLE HYGROSCOPE IN WATER AND AN ACTIVE INGREDIENT, IN PARTICULAR CIMETIDINE

机译：包含西米替丁的颗粒外赋形剂，水中的不溶性水份和活性成分的药物组合物的制备过程

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摘要

A pharmaceutical chewable tablet composition comprising: (i) granules containing a therapeutically active substance; and (ii) an extragranular water-insoluble hygroscopic excipient in an amount of 5% to 15% by weight of the total weight of the tablet. Particular therapeutically active substances include cimetidine and examples of suitable hygroscopic excipients include microcrystalline cellulose and powdered cellulose.

机译：药物可咀嚼片剂组合物，其包含：（i）含有治疗活性物质的颗粒;和（ii）粒外不溶于水的吸湿性赋形剂，其量为片剂总重量的5％至15％。特定的治疗活性物质包括西咪替丁，合适的吸湿性赋形剂的例子包括微晶纤维素和粉状纤维素。

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公开/公告号PT90466A

专利类型
公开/公告日1989-11-30

原文格式PDF
申请/专利权人 SMITH KLINE & FRENCH LAB. LTD.;
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申请/专利号PT19890090466
发明设计人 GORDON FRANCE;GRAHAM STANLEY LEONARD;
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申请日1989-05-04
分类号A61K9/00;A61K47/00;A61K31/415;
国家 PT
入库时间 2022-08-22 06:17:47

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