首页> 外国专利> New polymers chelating, their preparation and their application, in particular in the field of medical, in order to pick up the metal ion in excess in the body, and as complexing agents for the preparation of reactants which can be used in the field of medical imaging

New polymers chelating, their preparation and their application, in particular in the field of medical, in order to pick up the metal ion in excess in the body, and as complexing agents for the preparation of reactants which can be used in the field of medical imaging

机译:新的聚合物螯合剂,它们的制备及其应用,特别是在医学领域,以吸收体内过量的金属离子,并作为络合剂制备反应物,可用于医学领域影像学

摘要

Chelating polymers characterised in that they contain units of general formula I: IMAGE in which R denotes -H or -CH3 and X denotes a group of formula IMAGE in which: a = 0 or 1, p is a number which can vary from 1 to 4, Y1 and Y2 denote -H and Z2 then denotes -CO2H; or else, p is a number equal to 1, Y2 denotes -H, Y1 denotes -CH2SH and Z2 then denotes -CO2H; or else p is a number equal to 3 or 4, Y1 and Y2 denote -H and Z2 denotes the group -CH(NH2)-CO2H; or else a = 1, p = 0 and each of Y2 and Z2 then denotes a -CO2H group; and the esters, salts and metal complexes of these polymers; their preparation and their application especially as complexing agents in the industrial or medical field, in particular for trapping the harmful or excess metal ions in the organism and for the preparation of diagnostic reagents for medical imaging.
机译:螯合聚合物,其特征在于它们包含通式I的单元:,其中R表示-H或-CH3,X表示通式的基团,其中:a = 0或1,p是可以从1到4,Y1和Y2表示-H,Z2表示-CO2H;否则,p为1,Y2为-H,Y1为-CH2SH,Z2为-CO2H。否则,p是等于3或4的数,Y 1和Y 2表示-H,Z 2表示基团-CH(NH 2)-CO 2 H;否则a = 1,p = 0,则Y2和Z2各自表示-CO2H基团;这些聚合物的酯,盐和金属络合物;它们的制备及其应用,特别是在工业或医学领域中作为络合剂,特别是用于将有害或过量的金属离子捕获在生物体内以及用于医学成像的诊断试剂的制备。

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