首页> 外国专利> Analogues of L-fucose, process for their preparation, their application for the preparation of glycals, anthracycline derivatives of the glycals and the use of the anthracyclines as medicaments

Analogues of L-fucose, process for their preparation, their application for the preparation of glycals, anthracycline derivatives of the glycals and the use of the anthracyclines as medicaments

机译:L-岩藻糖的类似物,其制备方法,其在制备糖类中的应用,该糖类的蒽环类衍生物以及蒽环类作为药物的用途

摘要

The present invention relates to new L-Fucose analogs, their method of preparation, the application of such analogs to the preparation of new glycals, anthracyclines obtained by using such glycals and utilization of such anthracyclines as drugs. The glycals are obtained from L-Fucose and/or its analogs having the formula (1') and have the formula (2), wherein R is an optionally substituted linear or branched alkyl group or an optionally substituted aryl group, whith the exception of a CH2OR group or a CH2OR3 group, R3 having the same meaning as R.
机译:本发明涉及新的L-岩藻糖类似物,它们的制备方法,这些类似物在制备新的糖类中的应用,通过使用这种糖类得到的蒽环类药物以及这种蒽环类药物作为药物的利用。从具有式(1')并且具有式(2)的L-岩藻糖和/或其类似物获得所述糖基,其中R为任选取代的直链或支链烷基或任选取代的芳基,但R 1为-。 CH2OR基团或CH2OR3基团,R3与R的含义相同。

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