METHOD OF DETERMINING THE CONCENTRATION OF PREGNANEDIOL GLUCURONIDE IN A WOMAN'S URINE AND TEST DEVICE FOR USE THEREIN

• 1. 一种测定血浆或尿液中D-山梨醇浓度的方法 [P] . 中国专利： CN102621267B . 2014.08.06
• 2. 一种测定血浆或尿液中D-山梨醇浓度的方法 [P] . 中国专利： CN102621267A . 2012-08-01
• 3. METHOD OF DETERMINING THE CONCENTRATION OF PREGNANEDIOL¹GLUCURONIDE IN A WOMAN'S URINE AND TEST DEVICE FOR USE¹THEREIN [P] . IE822123L . 1983-03-23

  机译： 测定妇女尿液中的孕烯醇二葡糖醛酸的浓度的方法及其中使用的试验装置

• 4. METHOD OF DETERMINING THE CONCENTRATION OF PREGNANEDIOL GLUCURONIDE IN FEMALE URINE, AND TEST DEVICE FOR USE THEREIN [P] . CA1182044A . 1985-02-05

  机译： 测定女性尿液中孕二烯醇葡萄糖醛的浓度的方法及其使用的试验装置

• 5. Method of determining pregnanediol in female urine and test device for use therein [P] . 美国专利： USRE32557E . 1987-12-08

  机译： 测定女性尿液中孕烷二醇的方法及其所用的测试装置

• 1. DEM Simulation to Determine the Influence on the Experimental Results of Tests of Iron Pellets When the Dimensions of the Test Device Are Varied [J] . Yerko Aguilera-Carvajal, Yonathan Tapia Robledo, Sebastián Perez Cortes 现代非线性理论与应用（英文） . 2021,第002期
• 2. A method to determine the shell layout scheme for equipment battlefield damage tests under artillery fire [J] . Cai Chen, Quan Shi, Zhi-feng You, 兵工学报（英文版） . 2021,第002期
• 3. Methods of Determining Antibiotic Concentrations in the Gastrointestinal Tract of Cattle [C] . Derek Foster Conference of the American^College^of^Veterinary^Internal^Medicine . 2016
• 4. Novel methods for micellar electrokinetic chromatography and preconcentration on traditional microfluidic devices and the fabrication and characterization of paper microfluidic devices. [D] . Hoeman, Kurt W. 2009
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• 6. Pilot observational prospective cohort study on the use of a novel home-based urinary pregnanediol 3-glucuronide (PDG) test to confirm ovulation when used as adjunct to fertility awareness methods (FAMs) stage 1 [O] . Rene Leiva, Marie McNamara-Kilian, Helen Niezgoda, 2019
• 7. Effect of Diuretics on the Aminoacid Content of the Serum and Urine: Quick Method Suitable as Screening Test to Determine Total alpha-Amino Nitrogen [R] . Braun, P., Hauk, M., Horvath, I., 1964

• 1. A multi-methodological approach to determine CO_2 and CH_4 fluxes and concentrations in solid waste disposal [J] . Barbara Nisi ,Franco Tasssi ,Giordano Montegrossi . 地球化学学报（英文） . 2006,第B08期
• 2. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 3. Onsite Performance Verification of DETERMINE^(TM) TB LAM Ag:A Rapid Diagnostic Test for Tuberculosis Screening in Urine [J] . Mounerou Salou ,Diyane Gloria Badjassem ,Sika Dossim . 医学微生物学（英文） . 2019,第3期
• 4. 柱前衍生、LC-MS/MS同时测定血浆中的孕二烯酮、依托孕烯和炔雌醇 [C] . 刘笑芬 ,丁存刚 ,葛庆华 . 中国药学杂志岛津杯第九届全国药物分析优秀论文评选交流会 . 2009
• 5. 孕甾-16-烯-3S，20S-二醇二乙酸酯的钯催化反应和Betamethasone中间体的合成 [A] . 刘振华 . 2009