首页> 外国专利> pharmaceutical preparation containing 5 - t - butyl - 3 - the island - (1 - (s) - ethoxycarbonyl-3-phenylpropyl) - l - alanylaa - 2,3 - dihydro - 1,3,4 - thiadiazol - 2 - (s) - carboxylic acid or derivatives thereofand procedure for its manufacture

pharmaceutical preparation containing 5 - t - butyl - 3 - the island - (1 - (s) - ethoxycarbonyl-3-phenylpropyl) - l - alanylaa - 2,3 - dihydro - 1,3,4 - thiadiazol - 2 - (s) - carboxylic acid or derivatives thereofand procedure for its manufacture

机译：含有5-叔丁基-3-岛-（1-（s）-乙氧基羰基-3-苯基丙基）-l-丙氨酰-2,3-二氢-1,3,4-噻二唑-2-（s的药物制剂）-羧酸或其衍生物及其制备方法

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摘要

There are described new pharmaceutical formulations and methods for their preparation. Formulations comprising 5-t-butyl-3-[N-(1-(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl]-2,3-dih ydro-1,3,4 -thiadiazole-2-(S)-carboxylic acid, and pharmaceutically acceptable salts, esters, esters and amides thereof, as active ingredient in admixture with a pharmaceutically acceptable adjuvant, diluent or carrier in a form suitable for compression into a tablet or a capsule suitable for oral administration are described. There is also provided a unit dose formulation comprising from 1 mu g to 1mg of the aforementioned active ingredient Also described are processes for the manufacture of a pharmaceutical formulations.

机译：描述了新的药物制剂及其制备方法。包含5-叔丁基-3- [N-（1-（S）-乙氧基羰基-3-苯基丙基）-L-丙氨酰] -2,3-二氢基-1,3,4-噻二唑-2-（描述了作为活性成分的S）-羧酸及其药学上可接受的盐，酯，酯和酰胺，与药学上可接受的佐剂，稀释剂或载体的混合物，其形式适于压制成适于口服的片剂或胶囊剂。还提供了包含1μg至1mg上述活性成分的单位剂量制剂。还描述了药物制剂的制备方法。

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公开/公告号DK541789D0

专利类型
公开/公告日1989-10-31

原文格式PDF
申请/专利权人 FISONS PLC.;
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申请/专利号DK19890005417
发明设计人 TAPLEY IAN ROBERT;
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申请日1989-10-31
分类号A61K31/425;
国家 DK
入库时间 2022-08-22 06:39:39

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