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Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode
Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode
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机译:增加以化学电离模式运行的四极离子阱质谱仪的动态范围和灵敏度的方法
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摘要
A method is disclosed for increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode. Prior to mass analysis, a prescan is performed with the ion trap and the ionization and reaction periods are adjusted to produce enough stored product or analyte ions to generate a good signal- to-noise ratio in the detection of trace amounts of analyte, yet not so many analyte ions that resolution in the mass spectrum is lost. A mass analysis scan is then performed with the ion trap using the ionization and reaction periods predetermined during the prescan.
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