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ISOLATED MOLLUSC IMMUNOGENE, PROCESS FOR PREPARING SAME, DIAGNOSTIC REAGENTS FOR HUMAN BILHARZIOSIS, SCHISTOSOMIASIS VACCINES AND IMMUNIZING COMPOSITIONS COMPRISING SAME.
ISOLATED MOLLUSC IMMUNOGENE, PROCESS FOR PREPARING SAME, DIAGNOSTIC REAGENTS FOR HUMAN BILHARZIOSIS, SCHISTOSOMIASIS VACCINES AND IMMUNIZING COMPOSITIONS COMPRISING SAME.
Glycoprotein extracted from molluscs, especially from Megathura crenulata, namely haemocyanin, which exhibits the same antigenic properties as the antigen 38 KD isolated from the surface of schistosomule of S. mansoni; its oligosaccharide epitope. Serum protecting against infections by S. mansoni, originating from a mammal immunised with the abovementioned mollusc haemocyanin or its oligosaccharide epitope. Immunogenic composition containing the said glycoprotein or its oligosaccharide epitope and its applications as a diagnostic reagent, vaccine against bilharziosis, immunising agent, and the like.
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