首页> 外国专利> A lactate dehydrogenase or an antibody which reacts with lactate dehydrogenase in human cancer cells for use in the treatment of cancer

A lactate dehydrogenase or an antibody which reacts with lactate dehydrogenase in human cancer cells for use in the treatment of cancer

机译:乳酸脱氢酶或与人类癌细胞中的乳酸脱氢酶反应的抗体,用于治疗癌症

摘要

The nature of the present invention is to provide compositions for use in a method of inhibiting the development of cancer cells in humans by restricting the biochemical reaction within these cells in a manner which prevents the spread of the neoplasm and result in necrosis of the cancerous tissue. This object is achieved in accordance with the invention by providing:(i) A lactate dehydrogenase (LDH) obtained from a primate other than the patient to be treated, for use in the treatment of human cancer patients having cancer cells which include LDH, or(ii) An antibody which reacts with the lactate dehydrogenase (LDH) in human cancer cells for use in inhibiting the growth of cancer cells in a human cancer patient.
机译:本发明的本质是提供用于以抑制肿瘤扩散并导致癌组织坏死的方式限制生化反应从而抑制人癌细胞生长的方法的组合物。 。根据本发明,该目的通过提供: (i)从除待治疗患者以外的灵长类动物中获得的乳酸脱氢酶(LDH),用于治疗具有以下癌细胞的人类癌症患者:包括LDH或 (ii)与人类癌细胞中的乳酸脱氢酶(LDH)反应的抗体,可用于抑制人类癌症患者的癌细胞生长。

著录项

  • 公开/公告号EP0266459A1

    专利类型

  • 公开/公告日1988-05-11

    原文格式PDF

  • 申请/专利权人 LAKATOS GEORGE C.;

    申请/专利号EP19860308553

  • 发明设计人 LAKATOS GEORGE C.;

    申请日1986-11-03

  • 分类号A61K37/50;C12N9/04;A61K39/395;C12N15/00;A61K43/00;C12P21/00;

  • 国家 EP

  • 入库时间 2022-08-22 06:55:06

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