首页> 外国专利> SOLUTION FOR PRESERVING BLOOD OR BLOOD PREPARATION AND PRESERVATION OF BLOOD OR BLOOD PREPARATION USING SAID SOLUTION

SOLUTION FOR PRESERVING BLOOD OR BLOOD PREPARATION AND PRESERVATION OF BLOOD OR BLOOD PREPARATION USING SAID SOLUTION

机译:保留血液或血液准备的解决方案,以及使用上述解决方案保存血液或血液准备的解决方案

摘要

PURPOSE:To produce a preserving solution for suppressing reduction in sodium and increase in potassium in plasma and increase in liberated hemoglobin followed by hemolysis, by adding glycerin and mannitol to an anticoagulant solution containing citric acid, sodium citrate and glucose. CONSTITUTION:An anticoagulant solution containing citric acid, sodium citrate and glucose is incorporated with glycerin and mannitol. The amounts of glycerin and mannitol are amounts to give 0.5-1.5w/v% glycerin and 0.2-1.0w/v% mannitol when blood or blood preparation is added to the solution. Preferably the preserving solution is further mixed with a substance (e.g. sodium phosphate) to become a metabolic energy source for blood or blood cell of blood preparation and a substance (e.g. adenine or adenosine) to maintain function of erythrocyte progressing deterioration with preservation. The preserving solution is added to blood or blood preparation and preserved at 0-2 deg.C lower temperature than a conventional preservation temperature preferably using a container having gas permeability.
机译:目的:通过向含有柠檬酸,柠檬酸钠和葡萄糖的抗凝溶液中添加甘油和甘露醇,制得一种抑制血浆中钠减少,钾增加,游离血红蛋白增加,然后溶血的防腐溶液。组成:含有柠檬酸,柠檬酸钠和葡萄糖的抗凝溶液与甘油和甘露醇混合。当将血液或血液制剂添加到溶液中时,甘油和甘露醇的量为得到0.5-1.5w / v%的甘油和0.2-1.0w / v%甘露醇的量。优选地,将保存溶液进一步与一种物质(例如磷酸钠)混合以成为血液或血液制品的血细胞的代谢能量源,并与一种物质(例如腺嘌呤或腺苷)混合以维持红细胞随着保存而进行性恶化的功能。将保存液添加到血液或血液制品中,并优选使用具有透气性的容器在比常规保存温度低0-2℃的温度保存。

著录项

  • 公开/公告号JPS6360931A

    专利类型

  • 公开/公告日1988-03-17

    原文格式PDF

  • 申请/专利权人 SATO NOBORU;

    申请/专利号JP19860204269

  • 发明设计人 SATO NOBORU;OKAZAKI NAOTO;HIYOSHI KATSUMI;

    申请日1986-08-29

  • 分类号A61K35/14;

  • 国家 JP

  • 入库时间 2022-08-22 07:04:18

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