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Microcapsules biodegradable of serum albumin, their preparation and their application in the in situ medicuments

机译:可微降解血清白蛋白的微胶囊,其制备及其在原位药物中的应用

摘要

The present invention relates to biodegradable microcapsules based on serum albumin, the preparation thereof and the application thereof to the release of drugs in situ. A feature of the microcapsules according to the present invention is that their wall consists of serum albumin, a portion of which is crosslinked by interfacial polymerization with the aid of an acylating bifunctional reagent, and the other, non-crosslinked portion of which is denatured by means of an alcohol.
机译:本发明涉及基于血清白蛋白的可生物降解的微胶囊,其制备方法及其在原位释放药物中的应用。根据本发明的微胶囊的特征在于其壁由血清白蛋白组成,其一部分通过酰化双功能试剂的界面聚合而交联,而另一部分非交联的部分则通过变性而变性。酒精的手段。

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