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Squarate dye conjugate, process for making it and its use in assay methods and kits

机译:方形染料偶联物,其制备方法及其在测定方法和试剂盒中的用途

摘要

Novel assays for ligands and receptors employing novel compounds that are conjugates of squarates dyes and members of a specific binding pair (sbp) are disclosed. The sbp members are selected from the group consisting of ligand and its complementary receptor. The sbp member is covalently or non-covalently bound to the squarate dye, which usually has an absorption maximum greater than 600 nanometers. The novel conjugates are employed in assays for determining the presence or amount of an sbp member analyte in a sample suspected of containing such analyte. Kits comprising such novel conjugates are also disclosed.
机译:公开了使用新颖化合物的配体和受体的新颖测定,所述新颖化合物是方酸染料和特定结合对(sbp)成员的缀合物。 sbp成员选自配体及其互补受体。 sbp成员共价或非共价结合至方形染料,该方形染料通常具有的最大吸收大于600纳米。该新型缀合物用于测定以确定怀疑含有此类分析物的样品中sbp成员分析物的存在或量。还公开了包含此类新型缀合物的试剂盒。

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