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NOVEL HETEROCYCLIC COMPOUND, MANUFACTURE AND REMEDY FOR ALLERGIC OR INFLAMMATORY DISEASE AND ENDOTOXIC AND TRAUMATICSHOCK SYMPTON
NOVEL HETEROCYCLIC COMPOUND, MANUFACTURE AND REMEDY FOR ALLERGIC OR INFLAMMATORY DISEASE AND ENDOTOXIC AND TRAUMATICSHOCK SYMPTON
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机译:新颖的杂环化合物,变应性或发炎性疾病以及内毒素和创伤性抽搐症状的制造和补救
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摘要
This invention provides a series of novel keto sulfones of formula I IMAGE in which the group =A- is selected from =C(Ra)- and =N- and the other radicals have the meanings defined in the following specification. The compounds of formula I are leukotriene antagonists. The invention also provides pharmaceutically acceptable salts of the formula I compounds; pharmaceutical compositions containing the formula I compound, or their salts, for use in the treatment of, for example, allergic or inflammatory diseases, or endotoxic or traumatic shock conditions; and processes for the manufacture of the formula I compounds, as well as intermediates for use in such manufacture.
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