首页> 外国专利> METHOD FOR PREPARING 20-DEOXO-23-DE(MYCINOSYLOXY)TYLOSIN ANTIBIOTICS,THE NOVEL 20-DEOXO-23-DE(MYCINOSLYLOXY)TYLOSIN DERIVATIVES,THEIR USE AS INTERMEDIATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

METHOD FOR PREPARING 20-DEOXO-23-DE(MYCINOSYLOXY)TYLOSIN ANTIBIOTICS,THE NOVEL 20-DEOXO-23-DE(MYCINOSLYLOXY)TYLOSIN DERIVATIVES,THEIR USE AS INTERMEDIATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

机译：制备20-deoxo-23-de（肌醇缩合）酪氨酸抗菌剂，新颖的20-deoxo-23-de（肌醇缩合）酪氨酸衍生物的方法，用作中间体和包含它们的药物组合物

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摘要

20-Dihydro-20-deoxy-23-de(mycinosyloxy)tylosin (20-deoxo-DMOT), specified 2'-acyl ester derivatives, and their acid addition salts are useful intermediates and antibacterial agents. Methods of preparing 20-deoxo-DMOT and 5-O-mycaminosyltylactone by fermentation of Streptomyces fradiae ATCC 31733 are included.

机译：特定的2'-酰基酯衍生物20-二氢-20-脱氧-23-脱（mycinosyloxy）tylosin（20-deoxo-DMOT）及其酸加成盐是有用的中间体和抗菌剂。包括通过发酵链霉菌ATCC 31733制备20-脱氧-DMOT和5-O-mycaminosyltylactone的方法。

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公开/公告号IL69093A

专利类型
公开/公告日1986-09-30

原文格式PDF
申请/专利权人 ELI LILLY AND COMPANY;
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申请/专利号IL19830069093
发明设计人
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申请日1983-06-28
分类号C07H17/06;C12P19/62;A61K31/71;
国家 IL
入库时间 2022-08-22 07:41:22

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