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PROCESS FOR STABILIZING PHYSIOLOGICALLY ACTIVE MATERIAL PREPARED BY RECOMBINAT DNA TECHNIQUE, AND FOR PREPARING AQUEOUS SOLUTION OR POWDER CONTAINING THIS MATERIAL
PROCESS FOR STABILIZING PHYSIOLOGICALLY ACTIVE MATERIAL PREPARED BY RECOMBINAT DNA TECHNIQUE, AND FOR PREPARING AQUEOUS SOLUTION OR POWDER CONTAINING THIS MATERIAL
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机译:稳定重组DNA技术制备的具有生理活性的材料以及制备包含该材料的水溶液或粉末的方法
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摘要
A method for stabilizing a physiologically active substance produced by recombinant DNA technique, which comprises adding an albumin to an aqueous solution or powder containing the physiologically active substance, and a stable aqueous solution or powder which contains the physiologically active substance and an effective amount of an albumin, said physiologically active substance having cytotoxic activity against L-M cells and being capable of inducing hemorrhagic necrosis of transplanted Meth A sarcoma in the BALB/c mouse. The aqueous solution or powder containing the physiologically active substance can be stored for a prolonged period of time without losing its activity, and is stable on freezing, thawing, lyophilization or the like.
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