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complexes of one or more flavanoliganer with one or more phospholipids and procedure for the manufacture of the complexes and pharmaceutical agents containing the complexes
complexes of one or more flavanoliganer with one or more phospholipids and procedure for the manufacture of the complexes and pharmaceutical agents containing the complexes
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机译：一种或多种黄烷醇与一种或多种磷脂的配合物，以及制备配合物和包含该配合物的药剂的方法
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摘要
The invention relates to novel compounds comprising lipophilic complexes of silybin, silidianin, and silicristin with phospholipids, and the preparation of these complexes by non-conventional methods. Absorption of the novel compounds in the gastrointestinal tract is appreciably greater, resulting in higher plasma levels than for the individual flavanolignans. The resulting improvement in the pharmacokinetic and pharmacological parameters is such that the substances can advantageously be used in the treatment of acute and chronic liver disease of toxic, metabolic or infective origin or of degenerative nature.
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