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To increase the fertility a herd of sheep or goats

机译:为了增加生育能力,一群绵羊或山羊

摘要

A method for increasing the fecundity of a flock of female sheep or goats comprising immunizing the animals in the flock against a steroidal androgen, such as 4-androstene-3, 17-dione or testosterone, or a steroidal oestrogen, such as oestrone, as by administering an immunogenic steroid/protein conjugate to the animals, to produce a mean steroid-binding antibody titre in the flock in the range of 1 in 500 to 1 in 3000 at the start of a mating period lasting at least twice the length of the average oestrous cycle for animals in the flock, and to maintain that titre so that it does not fall outside the range 1 in 200 to 1 in 2000 at the conclusion of the mating period, the overall decline in the titre being no more than 75% during the mating period. The antibody response to suitable immunogens is controlled by the time elapsing between primary and secondary immunizations and by the molar ratio of the steroid derivative to the protein when immunization is brought about by administration of an immunogenic steroid/protein conjugate.
机译:一种增加雌性绵羊或山羊群的繁殖力的方法,该方法包括使该群动物免疫类固醇雄激素,例如4-雄甾烯-3、17-二酮或睾丸激素,或类固醇雌激素,例如雌酮,例如通过向动物施用免疫原性类固醇/蛋白质偶联物,在交配期开始时,在鸡群中产生平均类固醇结合抗体滴度,范围为500的三分之一至3000的三分之一,持续时间至少是母体长度的两倍。交配期结束时鸡群中动物的平均雌性周期,并保持该效价,以使其不超出2000年的200:1范围,总效价下降不超过75%在交配期间。当通过施用免疫原性类固醇/蛋白质缀合物进行免疫时,通过对初次和二次免疫之间的时间间隔以及类固醇衍生物与蛋白质的摩尔比来控制对合适免疫原的抗体应答。

著录项

  • 公开/公告号FR2474867B1

    专利类型

  • 公开/公告日1984-12-28

    原文格式PDF

  • 申请/专利权人 COMMONWEALTH SCIENTIFIC INDUSTRI;

    申请/专利号FR19810002269

  • 发明设计人

    申请日1981-02-05

  • 分类号A61K39/00;A01K67/00;

  • 国家 FR

  • 入库时间 2022-08-22 07:56:19

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