首页> 外国专利> 2,5-DICETOGLUCONIC ACID ENZYME REDUCTASE, 2,5-DKG REDUCTASE PREPARATION PROCESS, ENZYME AND PROTEIN WITH 2,5-DKG REDUCTASE ACTIVITY, 2,5-DKG CONVERTING PROCESS IN 2-KLG, PREPARATION PROCESS REPLICABLE EXPRESSION VEHICLE, EXPRESSION VECTOR AND VEHICLE, CELL CULTURE OR HOST CELLS, CELL CULTURE OR RECOMBINANT CELL, MICROORGANISM, AND COMMON METABOLITE CONVERSION PROCESS IN 2-KLG.

2,5-DICETOGLUCONIC ACID ENZYME REDUCTASE, 2,5-DKG REDUCTASE PREPARATION PROCESS, ENZYME AND PROTEIN WITH 2,5-DKG REDUCTASE ACTIVITY, 2,5-DKG CONVERTING PROCESS IN 2-KLG, PREPARATION PROCESS REPLICABLE EXPRESSION VEHICLE, EXPRESSION VECTOR AND VEHICLE, CELL CULTURE OR HOST CELLS, CELL CULTURE OR RECOMBINANT CELL, MICROORGANISM, AND COMMON METABOLITE CONVERSION PROCESS IN 2-KLG.

机译：2,5-二葡萄糖酸还原酶，2,5-DKG还原酶的制备过程，具有2,5-DKG还原酶活性的酶和蛋白质，2-KLG中的2,5-DKG转化过程，制备过程可复制的表达载体，表达载体2-KLG中的汽车，细胞，细胞培养或宿主细胞，细胞培养或重组细胞，微生物以及常见的代谢转化过程。

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摘要

A protein having 2,5-diketogluconic acid (2,5-DKG) reductase activity is produced by recombinant host cells. This can be used to convert 2,5-DKG stereoselectively into 2-keto-L-gulonic acid (2-KLG) which is a useful intermediate in the production of ascorbic acid (vitamin C).

机译：通过重组宿主细胞产生具有2，5-二酮葡萄糖酸（2，5-DKG）还原酶活性的蛋白质。可用于将2，5-DKG立体选择性地转化为2-酮-L-古洛糖酸（2-KLG），这是生产抗坏血酸（维生素C）的有用中间体。

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公开/公告号BR8403146A

专利类型
公开/公告日1985-02-12

原文格式PDF
申请/专利权人 GENENTECH INC.;
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申请/专利号BR19848403146
发明设计人 DAVID AARON ESTELL;ROBERT ALAN LAZARUS;DAVID RICHARD LIGHT;JEFFREY VEACH MILLER;WILLIAM HARRY RASTETTER;
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申请日1984-06-27
分类号C12N9/00;C12N15/00;
国家 BR
入库时间 2022-08-22 08:19:29

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