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BOEHRINGER INGELHEIM INTERNATIONAL

机译:勃林格殷格翰国际公司

摘要

This invention relates to a compound of the formula IMAGE (I) wherein R1, R2, R3, and R4, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl or alkoxy group of from 1 to 6 carbon atoms; R5 and R6, which may be the same or different, each represent a hydrogen atom, an alkyl group of from 1 to 6 carbon atoms, or an alkenyl group of from 3 to 6 carbon atoms, or R5 and R6 together with the nitrogen atom to which they are attached represent a pyrrolidino, piperidino, or morpholino group; and X represents oxygen, sulfur, or a methylene group, or a non-toxic, pharmacologically acceptable acid addition salt thereof, or a racemate, enantiomer, or mixture of enantiomers thereof. The compounds of Formula I are useful in pharmaceutical compositions for treating bronchial asthma and allergic bronchitis.
机译:本发明涉及式(I)的化合物,其中R 1,R 2,R 3和R 4可以相同或不同,分别表示氢或卤素原子或1至1的烷基或烷氧基。 6个碳原子; R 5和R 6可以相同或不同,分别代表氢原子,1至6个碳原子的烷基或3至6个碳原子的烯基,或R 5和R 6与氮原子一起它们所连接的代表吡咯烷基,哌啶子基或吗啉代基团; X表示氧,硫或亚甲基,或其无毒的,药理学上可接受的酸加成盐,或外消旋体,对映异构体或对映异构体的混合物。式I化合物可用于治疗支气管哮喘和过敏性支气管炎的药物组合物中。

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