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New derivatives of 1,2,4 -, their process of manufacture and their application as a antifecondants agents and to pharmaceutical compositions
New derivatives of 1,2,4 -, their process of manufacture and their application as a antifecondants agents and to pharmaceutical compositions
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机译:1,2,4-的新衍生物,其制备方法及其在抗抑con剂中的应用以及在药物组合物中的应用
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摘要
Novel 1,2,4-triazole derivatives are described having the following formula CHEM wherein R represents hydrogen or methyl, R1 stands for hydrogen or (C1-C4)alkyl, or R and R1 taken together may represent a further bond between the carbon atom and the oxygen atom, R2 and R4 each independently, represent hydrogen, chloro, fluoro, bromo, (C1-C4)alkyl or (C1-C4)alkoxy, R3 stands for (C1-C4)alkyl, (C1-C4)alkoxy, allyloxy propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R3 and R4 taken together may represent a methylenedioxy group. Also described is a process for their manufacture. Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredient are also claimed.
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